Publications논문

Dual-functional carbon nanotube yarn supercapacitor for real-time reactive oxygen species monitoring and sustainable energy supply in implantable device 새 글 수정됨
2024-11-28 13:35:58 조회수27
Taegyu Park, Dong Yeop Lee, Jung Ki Jo, Seon Jeong Kim, Yongwoo Jang Department of Medical and Digital Engineering, College of Engineering, Hanyang University, Seoul, 04736, South Korea Department of Pharmacology, College of Medicine, Hanyang University, Seoul, 04736, South Korea 원문 링크 : https://doi.org/10.1016/j.jpowsour.2024.235540

Abstract

 Smart stents integrate embedded sensors and advanced technology, providing a real-time diagnostic feedback, particularly for detection of thrombotic events. A continuous monitoring reactive oxygen species (ROS) in blood vessels is crucial for cardiovascular disease. The provision of a continuous power supply to sensors integrated within blood vessels is challenging. This study introduces a novel device that combines a sensor and supercapacitor, functioning as a ROS sensor and enabling continuous charging and discharging within blood vessels. This device uses yarn-shaped electrodes integrated with cytochrome c and carbon nanotubes (Cyt.c/CNT). The Cyt.c/CNT electrode exhibits a high specificity to ROS with an sensitivity (49.02 μA μM−1 cm−2), as a real-time biosensor for monitoring of cellular ROS levels in living cells. In addition, it exhibited an energy storage performance of 257.95 mF cm−2 as a supercapacitor and maintained a stable performance during 10,000 repeated cycles in various biofluids. Notably, the integration of the Cyt.c/CNT electrode with an enzymatic biofuel cell enables continuous charging and discharging in a biofluid, making it a promising system for in-vivo applications. This study presents the potential of Cyt.c for ROS sensing as well as its potential as an energy storage system, showing new possibilities for implantable devices for cardiovascular diseases.

 
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