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DNA Hydrogel Fiber with Self-Entanglement Prepared by Using an Ionic Liquid
2008-02-20 10:29:12 조회수1542
Chang Kee Lee, Su Ryon Shin, Sun Hee Lee, Ju-Hong Jeon, Insuk So, Tong Mook Kang, Sun I. Kim, Ji Young Mun, Sung-Sik Han, Geoffrey M. Spinks, Gordon G. Wallace, Seon Jeong Kim (1) Bio-Artificial Muscle Department of Biomedical Engineering Hanyang University, Seoul (Korea) (2) Department of Physiology Seoul National University, Seoul (Korea) (3) Department of Physiology Sungkyunkwan University, Suwon (Korea) (4) School of Life Sci. & Biotech. Korea University, Seoul (Korea) (5) ARC Centre of Excellence for Electromaterials Science University of Wollongong, NSW (Australia) 원문 링크 : http://onlinelibrary.wiley.com/doi/10.1002/anie.200704600/abstract

Abstract

A hydrogel fiber made entirely of DNA without any covalent cross-links, composed of intertwined toroid entanglements of flexible DNA strands (see scheme), was prepared by a one-step wet-spinning method with a hydrophilic ionic liquid as the condensing agent and coagulation solvent. The internal structure of the fiber was a disordered arrangement of strands with a B-DNA form. The fiber was also stable in various aqueous solutions.


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